Cargando…

Transcriptional regulatory networks underlying gene expression changes in Huntington's disease

Transcriptional changes occur presymptomatically and throughout Huntington's disease (HD), motivating the study of transcriptional regulatory networks (TRNs) in HD. We reconstructed a genome‐scale model for the target genes of 718 transcription factors (TFs) in the mouse striatum by integrating...

Descripción completa

Detalles Bibliográficos
Autores principales: Ament, Seth A, Pearl, Jocelynn R, Cantle, Jeffrey P, Bragg, Robert M, Skene, Peter J, Coffey, Sydney R, Bergey, Dani E, Wheeler, Vanessa C, MacDonald, Marcy E, Baliga, Nitin S, Rosinski, Jim, Hood, Leroy E, Carroll, Jeffrey B, Price, Nathan D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868199/
https://www.ncbi.nlm.nih.gov/pubmed/29581148
http://dx.doi.org/10.15252/msb.20167435