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Stop codon readthrough generates a C-terminally extended variant of the human vitamin D receptor with reduced calcitriol response

Although stop codon readthrough is used extensively by viruses to expand their gene expression, verified instances of mammalian readthrough have only recently been uncovered by systems biology and comparative genomics approaches. Previously, our analysis of conserved protein coding signatures that e...

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Detalles Bibliográficos
Autores principales: Loughran, Gary, Jungreis, Irwin, Tzani, Ioanna, Power, Michael, Dmitriev, Ruslan I., Ivanov, Ivaylo P., Kellis, Manolis, Atkins, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2018
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868278/
https://www.ncbi.nlm.nih.gov/pubmed/29386352
http://dx.doi.org/10.1074/jbc.M117.818526