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Pancreatic cancer cell lines as patient-derived avatars: genetic characterisation and functional utility
OBJECTIVE: Pancreatic ductal adenocarcinoma (PDAC) is a therapy recalcitrant disease with the worst survival rate of common solid tumours. Preclinical models that accurately reflect the genetic and biological diversity of PDAC will be important for delineating features of tumour biology and therapeu...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868284/ https://www.ncbi.nlm.nih.gov/pubmed/28073890 http://dx.doi.org/10.1136/gutjnl-2016-313133 |