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Pancreatic cancer cell lines as patient-derived avatars: genetic characterisation and functional utility

OBJECTIVE: Pancreatic ductal adenocarcinoma (PDAC) is a therapy recalcitrant disease with the worst survival rate of common solid tumours. Preclinical models that accurately reflect the genetic and biological diversity of PDAC will be important for delineating features of tumour biology and therapeu...

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Detalles Bibliográficos
Autores principales: Knudsen, Erik S, Balaji, Uthra, Mannakee, Brian, Vail, Paris, Eslinger, Cody, Moxom, Christopher, Mansour, John, Witkiewicz, Agnieszka K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868284/
https://www.ncbi.nlm.nih.gov/pubmed/28073890
http://dx.doi.org/10.1136/gutjnl-2016-313133