Epimerization-free access to C-terminal cysteine peptide acids, carboxamides, secondary amides, and esters via complimentary strategies

C-Terminal cysteine peptide acids are difficult to access without epimerization of the cysteine α-stereocenter. Diversification of the C-terminus after solid-phase peptide synthesis poses an even greater challenge because of the proclivity of the cysteine α-stereocenter to undergo deprotonation upon...

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Detalles Bibliográficos
Autores principales: Arbour, Christine A., Kondasinghe, Thilini D., Saraha, Hasina Y., Vorlicek, Teanna L., Stockdill, Jennifer L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868297/
https://www.ncbi.nlm.nih.gov/pubmed/29629104
http://dx.doi.org/10.1039/c7sc03553e

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868297/
https://www.ncbi.nlm.nih.gov/pubmed/29629104
http://dx.doi.org/10.1039/c7sc03553e

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