H(2)O(2)-responsive and plaque-penetrating nanoplatform for mTOR gene silencing with robust anti-atherosclerosis efficacy

The mammalian target of rapamycin (mTOR) that controls autophagy and lipid metabolism is pivotal for atherosclerosis initiation and progression. Although blocking the mTOR function with rapamycin and its analogs may stimulate autophagy and consequently attenuate lipid storage and atherosclerotic les...

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Detalles Bibliográficos
Autores principales: Gao, Wen, Zhao, Yujie, Li, Xiang, Sun, Yuhui, Cai, Michelle, Cao, Wenhua, Liu, Zhenhua, Tong, Lili, Cui, Guanwei, Tang, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868311/
https://www.ncbi.nlm.nih.gov/pubmed/29629115
http://dx.doi.org/10.1039/c7sc03582a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868311/
https://www.ncbi.nlm.nih.gov/pubmed/29629115
http://dx.doi.org/10.1039/c7sc03582a

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