Molecular Mechanisms of Human Disease Mediated by Oncogenic and Primary Immunodeficiency Mutations in Class IA Phosphoinositide 3-Kinases

The signaling lipid phosphatidylinositol 3,4,5, trisphosphate (PIP(3)) is an essential mediator of many vital cellular processes, including growth, survival, and metabolism. PIP(3) is generated through the action of the class I phosphoinositide 3-kinases (PI3K), and their activity is tightly control...

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Detalles Bibliográficos
Autores principales: Dornan, Gillian L., Burke, John E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868324/
https://www.ncbi.nlm.nih.gov/pubmed/29616047
http://dx.doi.org/10.3389/fimmu.2018.00575

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868324/
https://www.ncbi.nlm.nih.gov/pubmed/29616047
http://dx.doi.org/10.3389/fimmu.2018.00575

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