Keratins Regulate p38MAPK-Dependent Desmoglein Binding Properties in Pemphigus

Keratins are crucial for the anchorage of desmosomes. Severe alterations of keratin organization and detachment of filaments from the desmosomal plaque occur in the autoimmune dermatoses pemphigus vulgaris and pemphigus foliaceus (PF), which are mainly caused by autoantibodies against desmoglein (Ds...

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Detalles Bibliográficos
Autores principales: Vielmuth, Franziska, Walter, Elias, Fuchs, Michael, Radeva, Mariya Y., Buechau, Fanny, Magin, Thomas M., Spindler, Volker, Waschke, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868517/
https://www.ncbi.nlm.nih.gov/pubmed/29616033
http://dx.doi.org/10.3389/fimmu.2018.00528

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868517/
https://www.ncbi.nlm.nih.gov/pubmed/29616033
http://dx.doi.org/10.3389/fimmu.2018.00528

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