Influence of ABCB1 and CYP3A5 gene polymorphisms on pharmacokinetics of apixaban in patients with atrial fibrillation and acute stroke

INTRODUCTION: Difficulties in non-vitamin K anticoagulant (NOAC) administration in acute stroke can be associated with changes in pharmacokinetic parameters of NOAC such as biotransformation, distribution, and excretion. Therefore, obtaining data on pharmacokinetics of NOAC and factors that affect i...

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Detalles Bibliográficos
Autores principales: Kryukov, Alexander Valerevich, Sychev, Dmitry Alekseevich, Andreev, Denis Anatolevich, Ryzhikova, Kristina Anatolievna, Grishina, Elena Anatolievna, Ryabova, Anastasia Vladislavovna, Loskutnikov, Mark Alekseevich, Smirnov, Valeriy Valerevich, Konova, Olga Dmitrievna, Matsneva, Irina Andreevna, Bochkov, Pavel Olegovich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868588/
https://www.ncbi.nlm.nih.gov/pubmed/29606886
http://dx.doi.org/10.2147/PGPM.S157111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868588/
https://www.ncbi.nlm.nih.gov/pubmed/29606886
http://dx.doi.org/10.2147/PGPM.S157111

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