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Sevoflurane post-conditioning attenuates traumatic brain injury-induced neuronal apoptosis by promoting autophagy via the PI3K/AKT signaling pathway

BACKGROUND: Sevoflurane post-conditioning exerts nerve-protective effects through inhibiting caspase-dependent neuronal apoptosis after a traumatic brain injury (TBI). Autophagy that is induced by the endoplasmic reticulum stress plays an important role in the secondary neurological dysfunction afte...

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Detalles Bibliográficos
Autores principales: He, Hefan, Liu, Weifeng, Zhou, Yingying, Liu, Yibin, Weng, Peiqing, Li, Yasong, Fu, Huangde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868589/
https://www.ncbi.nlm.nih.gov/pubmed/29606856
http://dx.doi.org/10.2147/DDDT.S158313