Trastuzumab- and Fab′ fragment-modified curcumin PEG-PLGA nanoparticles: preparation and evaluation in vitro and in vivo

INTRODUCTION: Nanoparticles (NPs) modified with bio-ligands represent a promising strategy for active targeted drug delivery to tumour. However, many targeted ligands, such as trastuzumab (TMAB), have high molecular weight, limiting their application for targeting. In this study, we prepared Fab’ (a...

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Detalles Bibliográficos
Autores principales: Duan, Dongyu, Wang, Aiping, Ni, Ling, Zhang, Liping, Yan, Xiuju, Jiang, Ying, Mu, Hongjie, Wu, Zimei, Sun, Kaoxiang, Li, Youxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868600/
https://www.ncbi.nlm.nih.gov/pubmed/29606874
http://dx.doi.org/10.2147/IJN.S153795

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868600/
https://www.ncbi.nlm.nih.gov/pubmed/29606874
http://dx.doi.org/10.2147/IJN.S153795

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