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Interactome analysis reveals ZNF804A, a schizophrenia risk gene, as a novel component of protein translational machinery critical for embryonic neurodevelopment

Recent genome-wide association studies identified over 100 genetic loci that significantly associate with schizophrenia (SZ). A top candidate gene, ZNF804A, was robustly replicated in different populations. However, its neural functions are largely unknown. Here we show in mouse that ZFP804A, the ho...

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Detalles Bibliográficos
Autores principales: Zhou, Y, Dong, F, Lanz, T A, Reinhart, V, Li, M, Liu, L, Zou, J, Xi, H S, Mao, Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868632/
https://www.ncbi.nlm.nih.gov/pubmed/28924186
http://dx.doi.org/10.1038/mp.2017.166