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Cigarette smoke exposure promotes differentiation of CD4(+) T cells toward Th17 cells by CD40–CD40L costimulatory pathway in mice

PURPOSE: This study aimed to investigate the impact of cigarette smoke exposure upon CD40–CD40L ligation between bone marrow-derived dendritic cells (BMDCs)and CD4(+)T cells, and to examine the effects of cigarette smoke exposure upon differentiation of CD4(+)T cells toward Th17 cells through blocka...

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Detalles Bibliográficos
Autores principales: Liang, Yi, Shen, Ying, Kuang, Liangjian, Zhou, Guang, Zhang, Longju, Zhong, Xiaoning, Zhang, Jianquan, Liu, Jifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868633/
https://www.ncbi.nlm.nih.gov/pubmed/29606863
http://dx.doi.org/10.2147/COPD.S155754