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Proton pump inhibitor-refractory gastroesophageal reflux disease: challenges and solutions
A significant percentage of patients with gastroesophageal reflux disease (GERD) will not respond to proton pump inhibitor (PPI) therapy. The causes of PPI-refractory GERD are numerous and diverse, and include adherence, persistent acid, functional disorders, nonacid reflux, and PPI bioavailability....
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868737/ https://www.ncbi.nlm.nih.gov/pubmed/29606884 http://dx.doi.org/10.2147/CEG.S121056 |