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Proton pump inhibitor-refractory gastroesophageal reflux disease: challenges and solutions

A significant percentage of patients with gastroesophageal reflux disease (GERD) will not respond to proton pump inhibitor (PPI) therapy. The causes of PPI-refractory GERD are numerous and diverse, and include adherence, persistent acid, functional disorders, nonacid reflux, and PPI bioavailability....

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Detalles Bibliográficos
Autores principales: Mermelstein, Joseph, Chait Mermelstein, Alanna, Chait, Maxwell M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868737/
https://www.ncbi.nlm.nih.gov/pubmed/29606884
http://dx.doi.org/10.2147/CEG.S121056