Genetic variants in cellular transport do not affect mesalamine response in ulcerative colitis

BACKGROUND AND AIMS: Mesalamine is commonly used to treat ulcerative colitis (UC). Although mesalamine acts topically, in vitro data suggest that intracellular transport is required for its beneficial effect. Genetic variants in mucosal transport proteins may affect this uptake, but the clinical rel...

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Detalles Bibliográficos
Autores principales: Moran, Christopher J., Huang, Hailiang, Rivas, Manuel, Kaplan, Jess L., Daly, Mark J., Winter, Harland S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868763/
https://www.ncbi.nlm.nih.gov/pubmed/29579042
http://dx.doi.org/10.1371/journal.pone.0192806

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868763/
https://www.ncbi.nlm.nih.gov/pubmed/29579042
http://dx.doi.org/10.1371/journal.pone.0192806

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