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Comparative oncology approach to drug repurposing in osteosarcoma

BACKGROUND: Osteosarcoma is an orphan disease for which little improvement in survival has been made since the late 1980s. New drug discovery for orphan diseases is limited by the cost and time it takes to develop new drugs. Repurposing already approved FDA-drugs can help overcome this limitation. A...

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Detalles Bibliográficos
Autores principales: Parrales, Alejandro, McDonald, Peter, Ottomeyer, Megan, Roy, Anuradha, Shoenen, Frank J., Broward, Melinda, Bruns, Tyce, Thamm, Douglas H., Weir, Scott J., Neville, Kathleen A., Iwakuma, Tomoo, Fulbright, Joy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868798/
https://www.ncbi.nlm.nih.gov/pubmed/29579058
http://dx.doi.org/10.1371/journal.pone.0194224