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Comparative oncology approach to drug repurposing in osteosarcoma
BACKGROUND: Osteosarcoma is an orphan disease for which little improvement in survival has been made since the late 1980s. New drug discovery for orphan diseases is limited by the cost and time it takes to develop new drugs. Repurposing already approved FDA-drugs can help overcome this limitation. A...
Autores principales: | Parrales, Alejandro, McDonald, Peter, Ottomeyer, Megan, Roy, Anuradha, Shoenen, Frank J., Broward, Melinda, Bruns, Tyce, Thamm, Douglas H., Weir, Scott J., Neville, Kathleen A., Iwakuma, Tomoo, Fulbright, Joy M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868798/ https://www.ncbi.nlm.nih.gov/pubmed/29579058 http://dx.doi.org/10.1371/journal.pone.0194224 |
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