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Assessment of viral methylation levels for high risk HPV types by newly designed consensus primers PCR and pyrosequencing

BACKGROUND: Measuring viral DNA methylation in human papillomavirus (HPV) infected women showed promise for accurate detection of high-grade cervical lesions and cancer. Methylation status has been widely investigated for HPV16, sporadically for other HPV types. METHODS: Objective of this methodolog...

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Detalles Bibliográficos
Autores principales: Gillio-Tos, Anna, Fiano, Valentina, Grasso, Chiara, Trevisan, Morena, Gori, Silvia, Mongia, Alessandra, De Marco, Laura, Ronco, Guglielmo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868804/
https://www.ncbi.nlm.nih.gov/pubmed/29579066
http://dx.doi.org/10.1371/journal.pone.0194619