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Assessment of viral methylation levels for high risk HPV types by newly designed consensus primers PCR and pyrosequencing
BACKGROUND: Measuring viral DNA methylation in human papillomavirus (HPV) infected women showed promise for accurate detection of high-grade cervical lesions and cancer. Methylation status has been widely investigated for HPV16, sporadically for other HPV types. METHODS: Objective of this methodolog...
Autores principales: | Gillio-Tos, Anna, Fiano, Valentina, Grasso, Chiara, Trevisan, Morena, Gori, Silvia, Mongia, Alessandra, De Marco, Laura, Ronco, Guglielmo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868804/ https://www.ncbi.nlm.nih.gov/pubmed/29579066 http://dx.doi.org/10.1371/journal.pone.0194619 |
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