Class I HDAC inhibition is a novel pathway for regulating astrocytic apoE secretion

Despite the important role of apolipoprotein E (apoE) secretion from astrocytes in brain lipid metabolism and the strong association of apoE4, one of the human apoE isoforms, with sporadic and late onset forms of Alzheimer’s disease (AD) little is known about the regulation of astrocytic apoE. Utili...

Descripción completa

Detalles Bibliográficos
Autores principales: Dresselhaus, Erica, Duerr, James M., Vincent, Fabien, Sylvain, Emily K., Beyna, Mercedes, Lanyon, Lorraine F., LaChapelle, Erik, Pettersson, Martin, Bales, Kelly R., Ramaswamy, Gayathri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868809/
https://www.ncbi.nlm.nih.gov/pubmed/29579087
http://dx.doi.org/10.1371/journal.pone.0194661

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868809/
https://www.ncbi.nlm.nih.gov/pubmed/29579087
http://dx.doi.org/10.1371/journal.pone.0194661

Ejemplares similares