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Characterization of noise in multistable genetic circuits reveals ways to modulate heterogeneity

Random fluctuations in the amount of cellular components like mRNA and protein molecules are inevitable due to the stochastic and discrete nature of biochemical reactions. If large enough, this so-called “cellular noise” can lead to random transitions between the expression states of a multistable g...

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Detalles Bibliográficos
Autores principales: Hortsch, Sayuri Katharina, Kremling, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868838/
https://www.ncbi.nlm.nih.gov/pubmed/29579101
http://dx.doi.org/10.1371/journal.pone.0194779