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Characterization of noise in multistable genetic circuits reveals ways to modulate heterogeneity
Random fluctuations in the amount of cellular components like mRNA and protein molecules are inevitable due to the stochastic and discrete nature of biochemical reactions. If large enough, this so-called “cellular noise” can lead to random transitions between the expression states of a multistable g...
Autores principales: | Hortsch, Sayuri Katharina, Kremling, Andreas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868838/ https://www.ncbi.nlm.nih.gov/pubmed/29579101 http://dx.doi.org/10.1371/journal.pone.0194779 |
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