Improved methods of DNA extraction from human spermatozoa that mitigate experimentally-induced oxidative DNA damage

Current approaches for DNA extraction and fragmentation from mammalian spermatozoa provide several challenges for the investigation of the oxidative stress burden carried in the genome of male gametes. Indeed, the potential introduction of oxidative DNA damage induced by reactive oxygen species, red...

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Detalles Bibliográficos
Autores principales: Xavier, Miguel J., Nixon, Brett, Roman, Shaun D., Aitken, Robert John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868848/
https://www.ncbi.nlm.nih.gov/pubmed/29579126
http://dx.doi.org/10.1371/journal.pone.0195003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868848/
https://www.ncbi.nlm.nih.gov/pubmed/29579126
http://dx.doi.org/10.1371/journal.pone.0195003

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