Comparative pharmacokinetics and safety assessment of transdermal berberine and dihydroberberine

The natural alkaloid berberine has been ascribed numerous health benefits including lipid and cholesterol reduction and improved insulin sensitivity in diabetics. However, oral (PO) administration of berberine is hindered by poor bioavailability and increasing dose often elicits gastro-intestinal si...

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Detalles Bibliográficos
Autores principales: Buchanan, Beth, Meng, Qingfang, Poulin, Mathieu-Marc, Zuccolo, Jonathan, Azike, Chike Godwin, Gabriele, Joseph, Baranowski, David Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868852/
https://www.ncbi.nlm.nih.gov/pubmed/29579096
http://dx.doi.org/10.1371/journal.pone.0194979

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868852/
https://www.ncbi.nlm.nih.gov/pubmed/29579096
http://dx.doi.org/10.1371/journal.pone.0194979

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