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Glycogen synthase kinase‐3β activity plays a key role in the antitumor effect of nafamostat mesilate in pancreatic cancer cells

Pancreatic cancer is often resistant to chemotherapy. We previously showed the efficacy of combination treatment using gemcitabine and nafamostat mesilate (FUT‐175) for patients with unresectable pancreatic cancer. However, the mechanisms that affect the sensitivity of FUT‐175 are not fully understo...

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Detalles Bibliográficos
Autores principales: Haruki, Koichiro, Shiba, Hiroaki, Shimada, Yohta, Shirai, Yoshihiro, Iwase, Ryota, Fujiwara, Yuki, Uwagawa, Tadashi, Ohashi, Toya, Yanaga, Katsuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868870/
https://www.ncbi.nlm.nih.gov/pubmed/29863120
http://dx.doi.org/10.1002/ags3.12025