Functional analysis after rapid degradation of condensins and 3D-EM reveals chromatin volume is uncoupled from chromosome architecture in mitosis

The requirement for condensin in chromosome formation in somatic cells remains unclear, as imperfectly condensed chromosomes do form in cells depleted of condensin by conventional methodologies. In order to dissect the roles of condensin at different stages of vertebrate mitosis, we have established...

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Detalles Bibliográficos
Autores principales: Samejima, Kumiko, Booth, Daniel G., Ogawa, Hiromi, Paulson, James R., Xie, Linfeng, Watson, Cara A., Platani, Melpomeni, Kanemaki, Masato T., Earnshaw, William C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868952/
https://www.ncbi.nlm.nih.gov/pubmed/29361541
http://dx.doi.org/10.1242/jcs.210187

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868952/
https://www.ncbi.nlm.nih.gov/pubmed/29361541
http://dx.doi.org/10.1242/jcs.210187

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