Mbf1 ensures Polycomb silencing by protecting E(z) mRNA from degradation by Pacman

Under stress conditions, the coactivator Multiprotein bridging factor 1 (Mbf1) translocates from the cytoplasm into the nucleus to induce stress-response genes. However, its role in the cytoplasm, where it is mainly located, has remained elusive. Here, we show that Drosophila Mbf1 associates with E(...

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Detalles Bibliográficos
Autores principales: Nishioka, Kenichi, Wang, Xian-Feng, Miyazaki, Hitomi, Soejima, Hidenobu, Hirose, Susumu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868998/
https://www.ncbi.nlm.nih.gov/pubmed/29523653
http://dx.doi.org/10.1242/dev.162461

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868998/
https://www.ncbi.nlm.nih.gov/pubmed/29523653
http://dx.doi.org/10.1242/dev.162461

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