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Dark Rearing Does Not Prevent Rod Oxidative Stress In Vivo in Pde6b(rd10) Mice
PURPOSE: In cyclic light-reared Pde6b(rd10) mice, rod cell oxidative stress contributes to the degenerative phenotype. Dark rearing Pde6b(rd10) mice slows but does not prevent atrophy. This suggests that outer retinal oxidative stress occurs in Pde6b(rd10) mice independent of light exposure, a hypot...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868999/ https://www.ncbi.nlm.nih.gov/pubmed/29625492 http://dx.doi.org/10.1167/iovs.17-22734 |