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Dark Rearing Does Not Prevent Rod Oxidative Stress In Vivo in Pde6b(rd10) Mice

PURPOSE: In cyclic light-reared Pde6b(rd10) mice, rod cell oxidative stress contributes to the degenerative phenotype. Dark rearing Pde6b(rd10) mice slows but does not prevent atrophy. This suggests that outer retinal oxidative stress occurs in Pde6b(rd10) mice independent of light exposure, a hypot...

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Detalles Bibliográficos
Autores principales:	Berkowitz, Bruce A., Podolsky, Robert H., Berri, Ali M., Dernay, Kristin, Graffice, Emma, Shafie-Khorassani, Fatema, Roberts, Robin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2018
Materias:	Retinal Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868999/ https://www.ncbi.nlm.nih.gov/pubmed/29625492 http://dx.doi.org/10.1167/iovs.17-22734

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