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ES cell-derived presomitic mesoderm-like tissues for analysis of synchronized oscillations in the segmentation clock

Somites are periodically formed by segmentation of the anterior parts of the presomitic mesoderm (PSM). In the mouse embryo, this periodicity is controlled by the segmentation clock gene Hes7, which exhibits wave-like oscillatory expression in the PSM. Despite intensive studies, the exact mechanism...

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Detalles Bibliográficos
Autores principales: Matsumiya, Marina, Tomita, Takehito, Yoshioka-Kobayashi, Kumiko, Isomura, Akihiro, Kageyama, Ryoichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869006/
https://www.ncbi.nlm.nih.gov/pubmed/29437832
http://dx.doi.org/10.1242/dev.156836