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ES cell-derived presomitic mesoderm-like tissues for analysis of synchronized oscillations in the segmentation clock
Somites are periodically formed by segmentation of the anterior parts of the presomitic mesoderm (PSM). In the mouse embryo, this periodicity is controlled by the segmentation clock gene Hes7, which exhibits wave-like oscillatory expression in the PSM. Despite intensive studies, the exact mechanism...
Autores principales: | Matsumiya, Marina, Tomita, Takehito, Yoshioka-Kobayashi, Kumiko, Isomura, Akihiro, Kageyama, Ryoichiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869006/ https://www.ncbi.nlm.nih.gov/pubmed/29437832 http://dx.doi.org/10.1242/dev.156836 |
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