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Neurexin and Neuroligin-based adhesion complexes drive axonal arborisation growth independent of synaptic activity

Building arborisations of the right size and shape is fundamental for neural network function. Live imaging in vertebrate brains strongly suggests that nascent synapses are critical for branch growth during development. The molecular mechanisms underlying this are largely unknown. Here we present a...

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Detalles Bibliográficos
Autores principales: Constance, William D, Mukherjee, Amrita, Fisher, Yvette E, Pop, Sinziana, Blanc, Eric, Toyama, Yusuke, Williams, Darren W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869020/
https://www.ncbi.nlm.nih.gov/pubmed/29504935
http://dx.doi.org/10.7554/eLife.31659