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Spatial and Single-Cell Transcriptional Profiling Identifies Functionally Distinct Human Dermal Fibroblast Subpopulations

Previous studies have shown that mouse dermis is composed of functionally distinct fibroblast lineages. To explore the extent of fibroblast heterogeneity in human skin, we used a combination of comparative spatial transcriptional profiling of human and mouse dermis and single-cell transcriptional pr...

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Detalles Bibliográficos
Autores principales: Philippeos, Christina, Telerman, Stephanie B., Oulès, Bénédicte, Pisco, Angela O., Shaw, Tanya J., Elgueta, Raul, Lombardi, Giovanna, Driskell, Ryan R., Soldin, Mark, Lynch, Magnus D., Watt, Fiona M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869055/
https://www.ncbi.nlm.nih.gov/pubmed/29391249
http://dx.doi.org/10.1016/j.jid.2018.01.016