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A Upf3b-mutant mouse model with behavioral and neurogenesis defects

Nonsense-mediated RNA decay (NMD) is a highly conserved and selective RNA degradation pathway that acts on RNAs terminating their reading frames in specific contexts. NMD is regulated in a tissue-specific and developmentally controlled manner, raising the possibility that it influences developmental...

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Detalles Bibliográficos
Autores principales: Huang, L, Shum, EY, Jones, SH, Lou, C-H, Chousal, JN, Kim, H, Roberts, AJ, Jolly, LA, Espinoza, J, Skarbrevik, DM, Phan, MH, Cook-Andersen, H, Swerdlow, NR, Gecz, J, Wilkinson, MF
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869067/
https://www.ncbi.nlm.nih.gov/pubmed/28948974
http://dx.doi.org/10.1038/mp.2017.173