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A Upf3b-mutant mouse model with behavioral and neurogenesis defects
Nonsense-mediated RNA decay (NMD) is a highly conserved and selective RNA degradation pathway that acts on RNAs terminating their reading frames in specific contexts. NMD is regulated in a tissue-specific and developmentally controlled manner, raising the possibility that it influences developmental...
Autores principales: | Huang, L, Shum, EY, Jones, SH, Lou, C-H, Chousal, JN, Kim, H, Roberts, AJ, Jolly, LA, Espinoza, J, Skarbrevik, DM, Phan, MH, Cook-Andersen, H, Swerdlow, NR, Gecz, J, Wilkinson, MF |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869067/ https://www.ncbi.nlm.nih.gov/pubmed/28948974 http://dx.doi.org/10.1038/mp.2017.173 |
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