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Viral metagenomics, protein structure, and reverse genetics: Key strategies for investigating coronaviruses

Viral metagenomics, modeling of protein structure, and manipulation of viral genetics are key approaches that have laid the foundations of our understanding of coronavirus biology. In this review, we discuss the major advances each method has provided and discuss how future studies should leverage t...

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Detalles Bibliográficos
Autores principales: Johnson, Bryan A., Graham, Rachel L., Menachery, Vineet D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869085/
https://www.ncbi.nlm.nih.gov/pubmed/29279138
http://dx.doi.org/10.1016/j.virol.2017.12.009