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Dysfunction of Protein Quality Control in Parkinsonism–Dementia Complex of Guam

Guam parkinsonism–dementia complex (G-PDC) is an enigmatic neurodegenerative disease that is endemic to the Pacific island of Guam. G-PDC patients are clinically characterized by progressive cognitive impairment and parkinsonism. Neuropathologically, G-PDC is characterized by abundant neurofibrillar...

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Detalles Bibliográficos
Autores principales: Verheijen, Bert M., Oyanagi, Kiyomitsu, van Leeuwen, Fred W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869191/
https://www.ncbi.nlm.nih.gov/pubmed/29615966
http://dx.doi.org/10.3389/fneur.2018.00173