The SGC beyond structural genomics: redefining the role of 3D structures by coupling genomic stratification with fragment-based discovery

The ongoing explosion in genomics data has long since outpaced the capacity of conventional biochemical methodology to verify the large number of hypotheses that emerge from the analysis of such data. In contrast, it is still a gold-standard for early phenotypic validation towards small-molecule dru...

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Detalles Bibliográficos
Autores principales: Bradley, Anthony R., Echalier, Aude, Fairhead, Michael, Strain-Damerell, Claire, Brennan, Paul, Bullock, Alex N., Burgess-Brown, Nicola A., Carpenter, Elisabeth P., Gileadi, Opher, Marsden, Brian D., Lee, Wen Hwa, Yue, Wyatt, Bountra, Chas, von Delft, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Review Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869235/
https://www.ncbi.nlm.nih.gov/pubmed/29118096
http://dx.doi.org/10.1042/EBC20170051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869235/
https://www.ncbi.nlm.nih.gov/pubmed/29118096
http://dx.doi.org/10.1042/EBC20170051

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