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Type I interferon receptor knockout mice as models for infection of highly pathogenic viruses with outbreak potential
Due to their inability to generate a complete immune response, mice knockout for type I interferon (IFN) receptors (Ifnar(–/–)) are more susceptible to viral infections, and are thus commonly used for pathogenesis studies. This mouse model has been used to study many diseases caused by highly pathog...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Science Press
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869239/ https://www.ncbi.nlm.nih.gov/pubmed/29511140 http://dx.doi.org/10.24272/j.issn.2095-8137.2017.052 |