Serotonergic Dysfunction in Amyotrophic Lateral Sclerosis and Parkinson's Disease: Similar Mechanisms, Dissimilar Outcomes

Amyotrophic lateral sclerosis (ALS) and Parkinson's disease (PD) share similar pathophysiological mechanisms. From a neurochemical point of view, the serotonin (5-hydroxytryptamine; 5-HT) dysfunction in both movement disorders—related to probable lesioning of the raphe nuclei—is profound, and,...

Descripción completa

Detalles Bibliográficos
Autores principales: Vermeiren, Yannick, Janssens, Jana, Van Dam, Debby, De Deyn, Peter P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869258/
https://www.ncbi.nlm.nih.gov/pubmed/29615862
http://dx.doi.org/10.3389/fnins.2018.00185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869258/
https://www.ncbi.nlm.nih.gov/pubmed/29615862
http://dx.doi.org/10.3389/fnins.2018.00185

Ejemplares similares