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Serotonergic Dysfunction in Amyotrophic Lateral Sclerosis and Parkinson's Disease: Similar Mechanisms, Dissimilar Outcomes

Amyotrophic lateral sclerosis (ALS) and Parkinson's disease (PD) share similar pathophysiological mechanisms. From a neurochemical point of view, the serotonin (5-hydroxytryptamine; 5-HT) dysfunction in both movement disorders—related to probable lesioning of the raphe nuclei—is profound, and,...

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Detalles Bibliográficos
Autores principales:	Vermeiren, Yannick, Janssens, Jana, Van Dam, Debby, De Deyn, Peter P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869258/ https://www.ncbi.nlm.nih.gov/pubmed/29615862 http://dx.doi.org/10.3389/fnins.2018.00185

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