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Structural Basis for the Specific Neutralization of Stx2a with a Camelid Single Domain Antibody Fragment

Background: Shiga toxin-producing Escherichia coli (STEC) are a subset of pathogens leading to illnesses such as diarrhea, hemolytic uremic syndrome and even death. The Shiga toxins are the main virulence factors and divided in two groups: Stx1 and Stx2, of which the latter is more frequently associ...

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Detalles Bibliográficos
Autores principales: Bernedo-Navarro, Robert Alvin, Romão, Ema, Yano, Tomomasa, Pinto, Joar, De Greve, Henri, Sterckx, Yann G.-J., Muyldermans, Serge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869396/
https://www.ncbi.nlm.nih.gov/pubmed/29494518
http://dx.doi.org/10.3390/toxins10030108