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The Replacement of five Consecutive Amino Acids in the Cyt1A Protein of Bacillus thuringiensis Enhances its Cytotoxic Activity against Lung Epithelial Cancer Cells

Cyt1A protein is a cytolytic protein encoded by the cyt gene of Bacillus thuringiensis subsp. israelensis (Bti) as part of the parasporal crystal proteins produced during the sporulation. Cyt1A protein is unique compared to the other endotoxins present in these parasporal crystals. Unlike δ-endotoxi...

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Detalles Bibliográficos
Autores principales: Nair, Kavita, Iskandarani, Ahmad, Al-Thani, Roda, Mohammad, Ramzi, Jaoua, Samir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869413/
https://www.ncbi.nlm.nih.gov/pubmed/29547530
http://dx.doi.org/10.3390/toxins10030125