DNA Vaccine-Encoded Flagellin Can Be Used as an Adjuvant Scaffold to Augment HIV-1 gp41 Membrane Proximal External Region Immunogenicity

Flagellin’s potential as a vaccine adjuvant has been increasingly explored over the last three decades. Monomeric flagellin proteins are the only known agonists of Toll-like receptor 5 (TLR5). This interaction evokes a pro-inflammatory state that impacts upon both innate and adaptive immunity. While...

Descripción completa

Detalles Bibliográficos
Autores principales: Ajamian, Lara, Melnychuk, Luca, Jean-Pierre, Patrick, Zaharatos, Gerasimos J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869493/
https://www.ncbi.nlm.nih.gov/pubmed/29495537
http://dx.doi.org/10.3390/v10030100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869493/
https://www.ncbi.nlm.nih.gov/pubmed/29495537
http://dx.doi.org/10.3390/v10030100

Ejemplares similares