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DNA Vaccine-Encoded Flagellin Can Be Used as an Adjuvant Scaffold to Augment HIV-1 gp41 Membrane Proximal External Region Immunogenicity

Flagellin’s potential as a vaccine adjuvant has been increasingly explored over the last three decades. Monomeric flagellin proteins are the only known agonists of Toll-like receptor 5 (TLR5). This interaction evokes a pro-inflammatory state that impacts upon both innate and adaptive immunity. While...

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Detalles Bibliográficos
Autores principales:	Ajamian, Lara, Melnychuk, Luca, Jean-Pierre, Patrick, Zaharatos, Gerasimos J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869493/ https://www.ncbi.nlm.nih.gov/pubmed/29495537 http://dx.doi.org/10.3390/v10030100

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