Proviruses with Long-Term Stable Expression Accumulate in Transcriptionally Active Chromatin Close to the Gene Regulatory Elements: Comparison of ASLV-, HIV- and MLV-Derived Vectors

Individual groups of retroviruses and retroviral vectors differ in their integration site preference and interaction with the host genome. Hence, immediately after infection genome-wide distribution of integrated proviruses is non-random. During long-term in vitro or persistent in vivo infection, th...

Descripción completa

Detalles Bibliográficos
Autores principales: Miklík, Dalibor, Šenigl, Filip, Hejnar, Jiří
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869509/
https://www.ncbi.nlm.nih.gov/pubmed/29517993
http://dx.doi.org/10.3390/v10030116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869509/
https://www.ncbi.nlm.nih.gov/pubmed/29517993
http://dx.doi.org/10.3390/v10030116

Ejemplares similares