Rifampin modulation of xeno‐ and endobiotic conjugating enzyme mRNA expression and associated microRNAs in human hepatocytes

Rifampin is a pleiotropic inducer of multiple drug metabolizing enzymes and transporters. This work utilized a global approach to evaluate rifampin effects on conjugating enzyme gene expression with relevance to human xeno‐ and endo‐biotic metabolism. Primary human hepatocytes from 7 subjects were t...

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Detalles Bibliográficos
Autores principales: Gufford, Brandon T., Robarge, Jason D., Eadon, Michael T., Gao, Hongyu, Lin, Hai, Liu, Yunlong, Desta, Zeruesenay, Skaar, Todd C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869567/
https://www.ncbi.nlm.nih.gov/pubmed/29610665
http://dx.doi.org/10.1002/prp2.386

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869567/
https://www.ncbi.nlm.nih.gov/pubmed/29610665
http://dx.doi.org/10.1002/prp2.386

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