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Conservation of direct dynamics in sterically hindered S(N)2/E2 reactions

Nucleophilic substitution (S(N)2) and base-induced elimination (E2), two indispensable reactions in organic synthesis, are commonly assumed to proceed under stereospecific conditions. Understanding the way in which the reactants pre-orient in these reactions, that is its stereodynamics, is essential...

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Detalles Bibliográficos
Autores principales: Carrascosa, Eduardo, Meyer, Jennifer, Michaelsen, Tim, Stei, Martin, Wester, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869569/
https://www.ncbi.nlm.nih.gov/pubmed/29629138
http://dx.doi.org/10.1039/c7sc04415a