Diastereodivergent asymmetric Michael-alkylation reactions using chiral N,N′-dioxide/metal complexes

A diastereodivergent asymmetric Michael-alkylation reaction between 3-chloro-oxindoles and β,γ-unsaturated-α-ketoesters has been achieved using L-RaPr(2)/Sc(OTf)(3) and L-PrPr(2)/Mg(OTf)(2) metal complexes as catalysts. Both rel-(1R,2S,3R) and rel-(1S,2S,3R) chiral spiro cyclopropane oxindoles were...

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Detalles Bibliográficos
Autores principales: Kuang, Yulong, Shen, Bin, Dai, Li, Yao, Qian, Liu, Xiaohua, Lin, Lili, Feng, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869575/
https://www.ncbi.nlm.nih.gov/pubmed/29629137
http://dx.doi.org/10.1039/c7sc02757e

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869575/
https://www.ncbi.nlm.nih.gov/pubmed/29629137
http://dx.doi.org/10.1039/c7sc02757e

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