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Topological estimation of signal flow in complex signaling networks

In a cell, any information about extra- or intra-cellular changes is transferred and processed through a signaling network and dysregulation of signal flow often leads to disease such as cancer. So, understanding of signal flow in the signaling network is critical to identify drug targets. Owing to...

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Detalles Bibliográficos
Autores principales: Lee, Daewon, Cho, Kwang-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869720/
https://www.ncbi.nlm.nih.gov/pubmed/29588498
http://dx.doi.org/10.1038/s41598-018-23643-5